Perbandingan Sputum Spontan dan Sputum Induksi dalam Pemeriksaan TCM Menggunakan Genexpert Pada Penderita Terduga Tuberculosis Paru

Abstract

Tuberculosis is a direct infectious disease caused by TB (Mycobacterium Tuberculosis) germs. The examination method that is widely used in TB endemic countries is microscopic examination, however this method has a low sensitivity. Use of the Rapid Molecular Test (TCM) with the Xpert MTB / RIF is fast and can simultaneously identify the presence of MTB and rifampin resistance. Objective: To compare sputum material and sputum induction as the best material in detecting the presence of Mycobacterium Tuberculosis on genexpert examination. Materials and methods: 3% -5% NaCl solution, sample reagent, TCM cartridge with Xpert MTB / RIF and TCM Tool with Xpert MTB / RIF. This study is a diagnostic test with a cross sectional design. The study sample consisted of 60 sputum samples from patients with suspected pulmonary tuberculosis whose diagnosis would be confirmed by genexpert examination. Results: Men had a greater percentage of 44.73% compared to women and the most age was adults (70%), the results of the TCM genexpert method using spontaneous sputum samples obtained a greater percentage of positive spontaneous sputum by 73%, The results of the TCM examination of the genexpert method using spontaneous sputum samples obtained a greater percentage of positive spontaneous sputum by 60% and the comparison between spontaneous and induced sputum found more positive results and there was no significant evidence of effectiveness between spontaneous sputum and induced sputum in genexpert in patients with suspected pulmonary tuberculosis. Conclusion: The data of pulmonary tuberculosis patients in males is greater than in females and there is no evidence of significant effectiveness between spontaneous and induced sputum in genexpert examination.